To unravel how the CHEK2 c.1100delC mutation leads to breast cancer development through genome analysis and a human breast model.
Project summary
To unravel how the CHEK2 c.1100delC mutation leads to breast cancer development through genome analysis and a human breast model. Hollestelle delves into the underlying mechanism by which cells with a hereditary CHEK2 mutation can develop into breast cancer. Knowledge of this mechanism can eventually lead to prevention and better treatment of this cancer.
Impact
Type the project impact here.
More detailed information
Principal Investigator:
Dr. Antoinette Hollestelle
Role Erasmus MC:
Coördinator
Department:
Oncology
Project website:
Not available
Funding Agency:
KWF
