Advancing Early Detection and Diagnosis of ICI-Mediated Myocarditis – CERTAINTY

Project summary

Immune checkpoint inhibitors (ICI) are effective cancer drugs. Unfortunately, they can cause inflammation of the heart, myocarditis. Currently, there is no strategy for identifying patients at risk and diagnostic methods are suboptimal. This results in delayed diagnosis, which can enhance the mortality rate. Therefore, this research will investigate new methods of early detection and non-invasive diagnosis of ICI-mediated myocarditis. Furthermore, implementation of brand-new techniques will also increase knowledge on the mechanism of disease. Taken together, the aim of this research is to identify which patients might be at risk and to diagnose them accordingly, improving patient care.