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ThyHeart: unravel cardiovascular sex-differences through thyroid hormone metabolites


Client :
Liquid Themes

ThyHeart: unravel cardiovascular sex-differences through thyroid hormone metabolites

Project summary

The reason for sex-differences in cardiovascular disease is not fully understood but hormonal differences may play a role. Thyroid dysfunction is common in the general population, especially in women. Thyroid hormone and its metabolites have shown clear cardiovascular effects in animal models, but this has not been studied in humans due to lack of a reliable measurement method.  This project uses a novel method to measure thyroid hormones and their metabolites to investigate their role in the difference in cardiovascular disease between men and women.

More detailed information

Principal Investigator:

Dr. L. Chaker

Role Erasmus MC:

Principal Investigator

Department:

Endocrinology and Epidemiology

Project website:

Funding Agency:

NWO