Targeting chromatin environment around DNA replication fork to destabilize tumor cell proliferation
Client :
Liquid Themes
Targeting chromatin environment around DNA replication fork to destabilize tumor cell proliferation
Project summary
Unregulated DNA replication can provide limitless proliferation potential to tumor cells. The mechanisms regulating DNA replication machinery are poorly understood. This research focuses on identifying the specific chromatin organization signatures during replication in cancer cells and target those to cause instability of DNA replication process in cancer cells.
More detailed information
Principal Investigator:
Dr. N. Taneja
Role Erasmus MC:
Principal Investigator
Department:
Molecular Genetics
Project website:
Funding Agency:
NWO
